Pregnancy education
Anemia During Pregnancy: Symptoms, Testing & Treatment
Feeling tired is so common in pregnancy that low iron can be easy to miss. This guide explains what anemia is, how it is found, and the treatment options, from food and iron tablets to IV iron when it is truly needed.
Written for families in Lakeland and Polk County by the Lakeland Birth & Gynecology team. Published November 1, 2026.
Understanding anemia during pregnancy
Anemia means your blood has less hemoglobin than it should. Hemoglobin is the protein in red blood cells that carries oxygen through your body. Your body needs iron to make it.
Iron deficiency and anemia are related but not the same. Iron deficiency means your iron stores are low. Anemia means hemoglobin has already dropped. You can be low in iron before you become anemic.
Why iron needs go up
During pregnancy your blood volume grows by about 40 to 50 percent. Your body also sends iron to the placenta and your baby, especially in the third trimester. Many people start pregnancy with low stores from heavy periods, a recent pregnancy or diet.
Normal blood dilution
The liquid part of your blood expands faster than red blood cells. This dilutes hemoglobin a little, which is a normal part of pregnancy. That is why pregnancy uses its own ranges for each trimester.
Not every anemia is from low iron
Iron deficiency is the most common cause, but anemia can also come from low folate or vitamin B12, inherited conditions such as thalassemia or sickle cell trait, or other health conditions. Finding the cause comes first.
Signs and symptoms
- Fatigue
- Weakness
- Dizziness
- Headaches
- Less energy for exercise
- Shortness of breath with activity
- Heart palpitations
Some people have no symptoms at all. Many of these feelings also overlap with normal pregnancy, so blood work is the reliable way to know.
How is anemia diagnosed during pregnancy?
Screening is part of routine prenatal care. ACOG recommends a complete blood count (CBC) in the first trimester and again around 24 to 28 weeks. Your provider may look at:
- Hemoglobin and hematocrit
- MCV and other red blood cell measures
- Ferritin, which reflects iron stores
- Serum iron and TIBC
- Transferrin saturation
- Other tests when needed, such as B12, folate or hemoglobin evaluation
Anemia thresholds differ by trimester, and results are always read together with your symptoms and history. Low ferritin can point to depleted iron stores. Other causes, such as vitamin deficiencies or inherited blood conditions, may need more testing. A lab number alone does not decide treatment.
Why treating anemia matters
Iron-deficiency anemia can leave you feeling drained. When it goes untreated, it is associated with postpartum anemia, preterm birth and low birth weight. These are not inevitable. Finding the cause and treating it supports your health during pregnancy and your recovery after birth.
Treatment options
Dietary iron
Iron-rich foods include lean red meat, poultry, fish, beans, lentils, tofu, spinach and iron-fortified cereals. Pairing them with vitamin C foods like citrus, strawberries or peppers helps absorption. Tea, coffee and calcium can reduce absorption when taken at the same time. Food alone is often not enough once iron is low.
Oral iron supplements
Iron tablets are commonly the first-line treatment for iron-deficiency anemia in pregnancy. Side effects can include nausea, constipation, stomach upset and dark stools. Your provider may adjust the dose or schedule, such as every-other-day dosing, and recheck labs after a few weeks.
Intravenous (IV) iron
IV iron may be considered when oral iron is not tolerated, does not work, is not absorbed well, or when your situation calls for a different approach, such as anemia found later in pregnancy. It is generally considered in the second or third trimester, not the first. IV iron is not routinely needed and is not better for every pregnant patient.
When might I need an iron infusion during pregnancy?
Before an infusion is recommended, your clinician will:
- Confirm that iron deficiency is the cause
- Review hemoglobin and iron studies
- Ask about your symptoms
- Consider how far along you are
- Review how you responded to earlier treatment
- Estimate how much iron you need
- Talk through risks and alternatives with you
Iron sucrose (Venofer®) is FDA-approved for iron-deficiency anemia in chronic kidney disease. Using it for iron deficiency in pregnancy is off-label. That means it requires an individual clinical decision and your informed consent.
Published studies of iron sucrose given after the first trimester are reassuring. It still carries possible risks, including allergic-type (hypersensitivity) reactions and low blood pressure. Infusions are given under clinical supervision with monitoring during and after treatment.
Iron infusions available at Lakeland Birth & Gynecology
- Iron Sucrose 100 mg
- $294
- Iron Sucrose 200 mg
- $394
- Iron Deficiency Consultation With Standard Labs
- $150
- Your clinician prescribes the dose. Patients do not choose a dose online.
- Some patients need a series of infusions.
- Infusion pricing includes administration and required monitoring.
- The $150 consultation includes standard labs: CBC, Ferritin, Serum iron, TIBC and transferrin saturation.
- Infusions are billed separately from consultations.
- Baseline labs are generally required within 30 days of starting a new treatment course.
- Outside provider orders can be reviewed and accepted when clinically appropriate.
Can I receive an iron infusion if I see another OB or midwife?
Yes. You do not need to transfer your prenatal care to us. If you have recent blood work and a valid infusion order from your OB/GYN or midwife, you can request a review. We may need additional assessment before treatment, and we can keep your provider updated with your permission. If you would like midwifery-led care, learn about our pregnancy and prenatal care.
Postpartum anemia
After birth, anemia can come from blood loss during delivery or from low iron that carried over from pregnancy. Common signs include deep tiredness, dizziness, a racing heartbeat, shortness of breath and trouble keeping up with recovery or feeding.
Oral iron is often the first option. IV iron may be considered when anemia is more significant, oral iron is not tolerated, or faster replacement is needed. Follow-up labs help make sure your levels recover.
When to seek urgent care
Call 911 or go to the nearest emergency room for fainting, chest pain, severe shortness of breath, a very fast heartbeat at rest, or heavy bleeding (soaking a pad an hour or passing large clots). Severe or unstable anemia needs emergency care, not an outpatient infusion. In pregnancy, also seek urgent care for decreased fetal movement, vaginal bleeding or leaking fluid.
Patient questions
How common is anemia during pregnancy?
Quite common. Iron deficiency is the leading cause of anemia in pregnancy, and many people start pregnancy with low iron stores. Routine prenatal blood work helps find it.
Is low ferritin the same as anemia?
No. Ferritin reflects your iron stores. Anemia means hemoglobin is low. You can have low ferritin before anemia develops, which is often called iron deficiency without anemia.
Can I have normal hemoglobin but low iron stores?
Yes. Iron stores can run low before hemoglobin drops. Ferritin and other iron studies can show this earlier, and your clinician can decide whether treatment makes sense.
How does anemia affect pregnancy?
It can cause tiredness and shortness of breath. Untreated iron-deficiency anemia is associated with postpartum anemia, preterm birth and low birth weight. These are not certain to happen, and finding and treating the cause helps.
When are iron levels checked?
ACOG recommends a complete blood count (CBC) in the first trimester and again around 24 to 28 weeks. Iron studies such as ferritin may be added when results or symptoms call for it.
What if I cannot tolerate oral iron?
Tell your prenatal provider. Changing the type of iron, the dose or the schedule sometimes helps. If oral iron still is not tolerated or does not work, IV iron may be discussed.
Are iron infusions safe during pregnancy?
Published studies of iron sucrose given after the first trimester are reassuring, but no treatment is risk free. Possible reactions include allergic-type reactions and low blood pressure, so infusions are given with clinical supervision and monitoring.
Can I receive iron infusions in the third trimester?
Often, yes, when a clinician confirms it is appropriate. IV iron is generally considered in the second or third trimester, and anemia found later in pregnancy is one reason it may be discussed.
How many iron infusions might I need?
It depends on your labs, body size and response. Some people need a series of infusions. Your clinician calculates your iron needs and prescribes the dose.
Can my existing OB prescribe my infusion?
Yes. You can keep your current OB/GYN or midwife. We can review a valid outside infusion order with recent labs. Additional assessment may be needed before treatment.
What happens if I remain anemic after delivery?
Postpartum anemia is treatable. Your provider may recommend oral iron or IV iron and will recheck labs. Follow-up matters because anemia can make recovery and feeding harder.
Wondering about your iron levels?
If you are pregnant or postpartum in Lakeland, Winter Haven, Bartow, Plant City or elsewhere in Polk County, we're happy to review your labs or help you get tested. Our practice is in Lakeland, Florida. Hours: Monday – Friday, by appointment. Call (863) 666-7555.
Looking for general IV therapy information? Visit our sister service, Lakeland IV + Wellness. Iron infusion requests stay here with Lakeland Birth & Gynecology.
